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¸ðÁø¾Æ ( Mo Jin-A ) - Çѱ¹º¸°ÇÀǷῬ±¸¿ø
¹ÚÁö¼÷ ( Park Ji-Suk ) - ÀÎÇÏ´ëÇб³º´¿ø °£È£ºÎ ¿ÀÇö¼ö ( Oh Hyun-Soo ) - ÀÎÇÏ´ëÇб³ °£È£Çаú
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Abstract
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Purpose: This study was conducted to synthesis the results of research on relationships of cognitive impairment with multi-dimensionalcorrelates of rheumatic disease through a systematic literature review and meta-analysis.
Methods: For the study purpose, 23studies were selected through a systematic process of searching the literature.
Results: The study results showed that among generalcharacteristics, age and education were the variables having a significant relationship with cognitive impairment. Among healthrisk factors, obesity appeared to have a significant positive relationship with cognitive impairment. For past history, diabetes and hypertensionwere shown to have a significant positive relationship with cognitive impairment. It was noted also that aPL, one of thephysiological factor, had significant association with cognitive impairment. None of the medication related factors had a significantrelationship with cognitive impairment. Results showed that among disease related factors, disease activity had the highest relationshipwith cognitive impairment. Depression, among psychological factors, was the only variable having a significant relationship withcognitive impairment.
Conclusion: The findings indicate that the variables strongly impacting on cognitive impairment in rheumaticdisease are depression and disease activity.
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KeyWords
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ÀÎÁöÀå¾Ö, ·ù¸¶Æ¼½ºÁúȯ, ü°èÀû °íÂû, ¸ÞŸºÐ¼®
Cognition disorders, Rheumatic diseases, Review, Meta-analysis
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